Autoimmune Conditions That Can Lead to Dry Eye Syndrome

by Nov 7, 2023

Dry eye syndrome is a common condition that occurs when the eyes do not produce enough tears or when the tears evaporate too quickly, resulting in dry, irritated, and uncomfortable eyes. While there can be various causes of dry eye syndrome, one significant factor is underlying autoimmune conditions. In this blog, we will explore three autoimmune conditions that commonly contribute to chronic dry eye syndrome: Sjogren’s syndrome, systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). We will also discuss the treatment options available to alleviate dry eye symptoms associated with these conditions.


Sjogren’s Syndrome

Sjogren’s syndrome is an autoimmune disorder that primarily affects the salivary and lacrimal glands, which are responsible for producing saliva and tears, respectively. In this condition, the immune system mistakenly attacks the glands, leading to reduced tear production and dry eyes. Other symptoms associated with Sjogren’s syndrome include dry mouth, fatigue, joint pain, and swelling.

The treatment approach for dry eyes caused by Sjogren’s syndrome may involve both systemic and topical therapies. Systemic treatment options include immunosuppressant medications, such as steroids or immunomodulators, to reduce inflammation and control the autoimmune response. Additionally, artificial tears, lubricating ointments, or gels can be used as topical treatments to alleviate dryness and provide relief.


Systemic Lupus Erythematosus (SLE)

Systemic lupus erythematosus, commonly known as lupus, is an autoimmune condition that can affect multiple organs in the body, including the eyes. Dry eyes are a frequent ocular manifestation in individuals with SLE. The exact cause of dry eyes in lupus is not well understood, but it is believed to involve inflammation of the lacrimal glands.

The treatment of dry eyes in SLE involves managing the underlying autoimmune condition. Corticosteroids or immune-suppressing medications may be prescribed to control inflammation and reduce symptoms. Additionally, using artificial tears or prescription eye drops that help promote tear production can be beneficial in relieving dry eye symptoms.


Rheumatoid Arthritis (RA)

Rheumatoid arthritis (RA) is an autoimmune condition characterized by chronic inflammation that primarily affects the joints. However, RA can also lead to systemic complications, including dry eye syndrome. Inflammatory mediators associated with RA can disrupt the normal lacrimal gland function, resulting in reduced tear production and dry eyes.

The management of dry eyes in individuals with RA focuses on both systemic and ocular treatments. Medications for RA, such as disease-modifying antirheumatic drugs (DMARDs), help control inflammation and reduce the progression of the joint disease. Topical treatments, including artificial tears, lubricating ointments, or prescription eye drops, are used to alleviate dry eye symptoms and maintain eye moisture.


Seeking Professional Assistance for Dry Eye Syndrome

If you experience persistent dry eye symptoms or suspect an underlying autoimmune condition, it is essential to consult with a healthcare professional, ideally an ophthalmologist or a rheumatologist. They can evaluate your symptoms, perform relevant tests, and diagnose any autoimmune condition that may be contributing to your dry eyes.

The treatment approach will depend on the specific autoimmune condition and the severity of your symptoms. Your healthcare provider will develop an individualized treatment plan that may include systemic medications to manage the autoimmune condition, as well as topical treatments to address dry eyes directly.


Our eye doctors at EyeDocs Family Eye Care in Brookville, OH excel in the prescription of glasses, contact lenses and the diagnosis of a variety of eye diseases. Call our optometrists at 937-770-1265 or schedule an eye exam appointment online if you would like to learn more about dry eye syndrome and the underlying autoimmune conditions. Our eye doctors, Dr. Kyle Maxam and Dr. Cara Wampler provide the highest quality optometry services and eye exams in Brookville, Ohio.

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